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Abstract The enzyme glucose isomerase used by Gist‐Brocades for the process of immobilization is derived from a strain of Actinoplanes missouriensis. The intracellular enzyme is fixed to the mycelium and as such immobilized.


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An ever-ambitious company Reinvention is in our blood (we are a science company, after all). From the depths of the Dutch State Mines over a century ago we've transformed ourselves into something truly bright: a global science-based company specializing in ensuring the world is healthier, happier and safer.


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Delft, NL, 03 Apr 2017 08:00 CEST. Royal DSM, a global science-based company active in health, nutrition and materials, today opens a new state-of-the-art biotechnology facility at its site in Delft to accelerate DSM's biotechnology research and development capabilities for applications in food and nutrition, feed, fuel, pharma and bio-based materials.


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2 International Regulatory Affairs, DSM/Gist-brocades, Delft, Netherlands Corresponding Author: International Regulatory Affairs, DSM/Gist-brocades B.V., Business Group, Anti-Infectives, PO Box 1, 2600 MA Delft, The Netherlands


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Through the $1.4 billion acquisition of Gist­ brocades {Delft, The Netherlands) by the chemicals firm DSM (Heerlen, The Neth-erlands), a new anti-biotics intermediates


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The sprawling industrial complex that is the Nederlandsche Gisten en Spiritusfabriek lies between the railway and the canals is not the most beautiful sight in Delft but nevertheless it has a fascinating history and an aspect that justifies its inclusion in this column.


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International Regulatory Affairs, DSM/Gist-brocades, Delft, Netherlands. Notes. International Regulatory Affairs, DSM/Gist-brocades B.V., Business Group, Anti-Infectives, PO Box 1, 2600 MA Delft, The Netherlands. Metrics and citations Metrics. Journals metrics. This article was published in Therapeutic Innovation & Regulatory Science.


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goals of a totally novel wastewater treatment at the Gist Brocades biotechnological factory in Delft. The concept developed by Sef Heijnen (Heijnen et al., 1991) was a series of fluidized bed reactors (vertical cylindrical columns of 18 m high and 5 m in diameter) with suspended flocs or granules of microorganisms initially attached to sand.


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During World War II researchers worked on penicillin. The code name Bacinol was used to keep the research secret from the Germans. [6] The research was done at the company Nederlandsche Gist- en Spiritusfabriek, Dutch Yeast and Spirits Factory, later becoming DSM Sinochem Pharmaceuticals, in Delft .


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In 1968 the Dutch Yeast and Spirits Factory merged with Brocades to form the Royal Gist-Brocades NV. In 1998 the Royal Gist-Brocades NV was taken over by multinational DSM. In 2019, DSM in Delft celebrated its 150 anniversary and being a front runner in biotechnological innovations with global impact.


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Building on the strong foundation of its predecessors Royal Dutch Yeast and Spirit Factory and Royal Gist-brocades, today's biotechnology competences and expertise rank DSM among the top three companies in the world in industrial biotechnology. 20% of DSM's total sales are derived from biotechnology.


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Gist-brocades is a major international biotechnology company with its main production facilities in Delft. Waste water from the various fermentation and chemical production processes is characterized by its high concentration and frequent fluctuation of pollution components.


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Building on the strong foundation of its predecessors Royal Dutch Yeast and Spirit Factory and Royal Gist-brocades, today's, biotechnology competences and expertise rank DSM among the top three companies in the world in industrial biotechnology. 20% of DSM's total sales are derived from biotechnology.


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In the early 1990s, the Gist Brocades Fermentation Company closed their pilot plant, leaving the reactor in our laboratory as the only confirmed source of anammox bacteria.. Delft University of.